What is cutaneous Pseudolymphoma?
Cutaneous pseudolymphoma refers to a heterogeneous group of benign reactive T- or B-cell lymphoproliferative processes of diverse causes that simulate cutaneous lymphomas clinically and/or histologically.
What is lymphocytoma?
Lymphocytoma cutis, or benign reactive lymphoid hyperplasia, is an inflammatory skin lesion that mimics clinically and histologically malignant lymphoma. Most cases are idiopathic, but they may also be triggered by multiple factors, such as insect bites, tattoos, injections and herpes zoster.
What is lymphoma cutis?
Cutaneous lymphoma, also known as lymphoma cutis, is when lymphoma involves the skin. It is characterized by a proliferation of lymphoid tissue. There are two main classes of lymphomas that affect the skin: Cutaneous T-cell lymphoma.
What does Pseudolymphoma look like?
Pseudolymphomatous drug eruption due to captopril, marked by erythematous to purple papules, patches, and plaques. This erythrodermic pseudolymphoma (T-cell pattern) typifies drug-induced pseudolymphoma, which is most often secondary to anticonvulsant therapy.
What is T cell hyperplasia?
Paracortical hyperplasia is the preferential stimulation of the T cell compartment. It is caused by an abnormal expansion of the interfollicular zones but is confined within the lymph node capsule. The population of the compartment is cytologically polymorphous.
How common is cutaneous T cell lymphoma?
CTCL is a rare form of T-cell lymphoma. There are about 3,000 new cases of CTCL in the U.S. each year, and about 16,000 – 20,000 Americans have mycosis fungoides.
What drugs cause Pseudolymphoma?
Anticonvulsants, typically phenytoin and carbamazepine, are the most frequent cause of drug-induced pseudolymphoma.
What is cutaneous T-cell lymphoma?
Cutaneous T-cell lymphoma 1 Overview. Cutaneous T-cell lymphoma (CTCL) is a rare type of cancer that begins in white blood cells called T cells (T lymphocytes). 2 Symptoms 3 Causes. The exact cause of cutaneous T-cell lymphoma isn’t known. In general, cancer begins when cells develop changes (mutations) in their DNA.
What is lymphocytoma cutis and what causes it?
What is lymphocytoma cutis? Lymphocytoma cutis is a rare pseudolymphoma that has also been known as ‘ cutaneous lymphoid hyperplasia ’ or ‘lymphadenosis benigna cutis’. It is a process that simulates a cutaneous lymphoma (blood cell cancer developing in the skin), but it behaves in a harmless manner. It appears to be a reactive process.
What is non mycosis fungoides cutaneous T-cell lymphoma?
–Non-mycosis fungoides cutaneous T-cell lymphoma (immunophenotyping, TCR gene rearrangement) –Polymorphous light eruption – plaque form (seasonal, photodistributed, pathology shows dermal edema, perivascular T-lymphocytic infiltrate).
What are the symptoms of T-cell lymphoma?
One of the most common forms of T-cell lymphoma is cutaneous T-cell lymphoma (CTCL), a general term for T-cell lymphomas that involve the skin. CTCL can also involve the blood, lymph nodes, and other internal organs. Symptoms can include dry skin, itching (which can be severe), a red rash, and enlarged lymph nodes.
